I agree with locking the first product to ADPD4200 and treating ADPD4101BCBZR7 as a future upscale platform. That matches the basic component-selection rule of choosing to the application need instead of overbuilding the first revision
Why this is a good decision
Lower IC cost
Best if the first goal is proving clinical signal value, not maximizing optical channel count.
Simpler architecture
Fewer available channels forces discipline in the sensor head and firmware.
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